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Home » Active Pharmaceuticals Ingredients » Chlorobutanol

Chlorobutanol

Product Name Chlorobutanol BP/EP/USP
Chemical Name 1,1,1-Trichloro-2-methylpropan-2-ol
CAS Number 57-15-8
Chemical Formula C4H7Cl3O
Molecular Mass 175.5 g/mol
Therapeutic Category Antibacterial

Specification of Chlorobutanol :

Test Specification
Characteristics White, crystalline powder or colourless crystals, sublimes readily
Solubility Slightly soluble in water, very soluble in alcohol, soluble in glycerol (85%)
Melting point Melts at about 78°C
Identification Test A,B&C;D
Test: Water content Not More Than 4.5 % w/w and 5.5%w/w
Appearance of solution A.50 % test solution should not be more opalescent than reference than suspension II & not more intensely coloured than reference solution BY5
Acidity NMT 1.0ml of 0.01M NaOH is required to change the colour of the bromothymol blue
Chloride Not More Than 100 PPM
Water content Between 4.5 % w/w and 5.5 % w/w
Sulphated Ash Not More Than 0.1 % w/w
Assay (on anhydrous basis) Not Less Than 98.0 % w/w and Not More Than 101.0 % w/w

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