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Yashica Pharmaceuticals

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Home » Active Pharmaceuticals Ingredients » Disulfiram

Disulfiram

Product Name Disulfiram BP/EP/USP
Chemical Name 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane
CAS Number 97-77-8
Chemical Formula C10H10N2S4
Molecular Mass 296.54 g/mol
Therapeutic Category -

Specification of Disulfiram :

Test Specification
Description A white to almost white crystalline powder
Solubility Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in alcohol
Identification
A) Melting range
B) By IR
C) By TLC

D) By chemical

Between 70º c and 73º c
The IR. Spectrum is concordant with spectrum obtained from Disulfiram working standard.
The principal spot obtained in the chromatogram with Disulfiram test solution should be similar in position and size to the principal spot obtained in the chromatogram with Disulfiram working standard
A yellow color develops which becomes greenish-yellow
Diethyldithiocarbamate NMT 150 ppm
Loss on drying NMT 0.5% w/w
Sulphated ash NMT 0.1%
Heavy metals NMT 20 ppm
Related substances By TL NMT 0.5%
Assay (ODB) Between 98.5% & 101 %

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