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Home » Active Pharmaceuticals Ingredients » Loratadine


Product Name Loratadine BP/EP/USP
Chemical Name Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate
CAS Number 79794-75-5
Chemical Formula C22H23ClN2O2
Molecular Mass 382.88 g/mol
Therapeutic Category antidepressants

Specification of Loratadine :

Test Specification
Description White off-white powder
Solubility Freely soluble in acetone, in chloroform, in methanol and in toluene, insoluble in water
A ) Infrared spectrum (In Mineral oil)


The IR absorption spectrum of the preparation of the test specimen, exhibits maxima only at the same wavelengths as that of a similar preparation of the corresponding Loratadine working standard

The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation as obtained in the assay
Melting point (°C) Between 132 and 137
Loss on drying (%, w/w) NMT 0.5
Residue on ignition (%,w/w) NMT 0.1
Heavy metals (%,w/w) NMT 0.001
Related compounds (By HPLC)
Related compounds A
Related compounds B
Each individual unknown impurity
Total impurities

NMT 0.1
NMT 0.1
NMT 0.1
NMT 0.3
Assay By HPLC (%w/w) (On dried basis) NLT 98.5 and NMT 101.0
Additional Tests
Residual solvent/Organic volatile impurities (By GC with HSS,ppm)

Tetrahydrofuran : NMT 500
Toluene : NMT 500
Di-isopropyl ether : NMT 500
Triethylamine : NMT 50

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Letrozole Intermediate

Letrozole is a White to yellowish, crystalline powder and used as an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.

NAME OF PRODUCT : Letrozole Intermediate
CAS NO 112809-51-5
Chemical Formula C17H11N5
MOL. WEIGHT 285.303 g/mol

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Product Name Niclosamide BP/EP/USP
Chemical Name 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
CAS Number 50-65-7
Chemical Formula C13H8Cl2N2O4 
Molecular Mass 327.12 g/mol
Therapeutic Category Anti-anthelmintic

Specification of Niclosamide :

Test Specification
Description Yellowish white or Yellowish, fine crystals
Solubility Practically insoluble in water, sparingly soluble in Acetone Slightly soluble in Ethanol
Identification Comparing with spectrum of Anhydrous Niclosamide CRS
Melting Range 227°C - 232°C
Loss on drying NMT 0.5% w/w
Chloride content NMT 500 ppm
Sulphated Ash NMT 0.1% w/w
5- Chlorosalicylic Acid The colour in the test solution is not more intense than that in the reference solution [60 ppm]
2- Chloro -4-Nitroaniline The colour in the test solution is not more intense than that in the reference solution [100 ppm]
Purity by HPLC NLT 98.0%
Sulphated ash NMT 0.1%
Assay 98% - 101%

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Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and fever reducer effects. It is a derivative of oxicam, closely related to piroxicam, and falls in the enolic acid group of NSAIDs.

CAS NO 71125-38-7
Molar mass 351.403 g/mol
Bioavailability 89%
Protein Binding  99.4%

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