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Home » Active Pharmaceuticals Ingredients » Oxyclozanide

Oxyclozanide

Product Name Oxyclozanide BP/EP/USP
Chemical Name 2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
CAS Number 2277-92-1
Chemical Formula C13H6Cl5NO3
Molecular Mass 401.46 g/mol
Therapeutic Category Anthelmintic

Specification of Oxyclozanide :

Test Specification
Nature A pale, cream colour odourless powder
Solubility Slightly soluble in water, freely soluble in acetone, soluble in ethanol (96%),slightly soluble in chloroform
Identification As per BP Vet
Melting Point About 208 ºC
Ionisable chlorine NMT 0.25%
Related substance by HPLC
A) Individual Impurity
B) Total Impurity

NMT 0.3%
NMT 1%
Loss on Drying (At 60ºC under vacuum) NMT 1% w/w
Moisture content NMT 0.5%
Sulphated Ash NMT 0.2% w/w
Assay (Dry Basis) NLT 98.00% & NMT 101.00%

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Olanzepine

Olanzapine is a Yellow Crystalline Powder and an atypical antipsychotic. It is used for the treatment of schizophrenia and bipolar disorder.

NAME OF PRODUCT : Olanzapine
CAS NO 132539-06-1
Chemical Formula C17H20N4S
MOL. WEIGHT 312.439 g/mol









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Orlistat Pellets

NAME OF PRODUCT : Orlistat Pellets
Description a white to off-white powder
Solubility Freely soluble in Chloroform. Insoluble in Water
Identification
a) By HPLC



b) By I.R. Absorption

The retention time of Orlistat peak in the sample chromatogram of assay test should match with that of laboratory standard.


The IR Spectrum of sample should be concordant with that of the laboratory standard.
Melting Range Between 40°C to 48°C
Water content(by KF Titration) NMT 1.00% W/W
Specific Optical Rotation (in Chloroform) Between -30.0° and -40.0°
Residue on Ignition NMT 0.20% W/W
Heavy Metals NMT 0.002% (20 ppm)
Related substances (by HPLC ) Isopentyl Analog
Dimethyl Orlistat
Any other single maximum impurity
Total Impurity
NMT 1.00%
NMT 1.00%
NMT 1.00%
NMT 3.00%
Assay Content of Orlistat(by HPLC) Between 95.0% W/W and 100% W/W

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