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Tramadol Hydrochloride Injection

The Yashidol Injection is a centrally acting analgesic and has an antitussive effect. In contrast to morphine, analgesic doses of Tramadol over a wide range have no respiratory depressant effect. Also gastrointestinal motility is less affected. Effects on the cardiovascular system tend to be slight. Each injection includes 50 mg of tramadol hydrochloride. The injection ampoules are delivered in tamper-proof packaging to maintain the quality during the transportation.

Composition:	Each mL contains: tramadol hydrochloride BP 50 mg
Category:	Opioid receptor agonist and enantiomer Noradrenaline reuptake inhibitor Analgesic
Molecular formula:	C16H26ClNO2
Molecular weight:	299.80
Indication:	Tramadol hydrochloride is an opioid analgesic. It also has noradrenergic and serotonergic properties that may contribute to its analgesic activity. Tramadol is used for moderate to severe pain.
Dosage & administration:	Yashidol injection is given by intravenous route. The intramuscular route may also be used. It may also be given by infusion or as part of patient-controlled analgesia system. A dose of 50 to 100 mg may be given every 4 to 6 hours by intramuscular or intravenous injection over 2 to 3 minutes or by intravenous infusion. For the treatment of postoperative pain, the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a total maximum (including the initial dose) of 250 mg in the first hour. Thereafter, doses are 50 to 100mg every 4 to 6 hours up to a total daily dose of 600 mg.
Contraindications:	Hypotension Alcohol and psychotropic intoxication Hypersensitivity
Adverse effects:	Nausea Vomiting and dizziness
Special precautions:	Alcohol Not to drive and operate machinery
Interactions:	Carbamazepine: A significant increase in tramadol metabolism. Hypnotics, tranquilizers and other Carbamazepine: A significant increase in tramadol metabolism. Hypnotics, tranquilizers and other Hypnotics, tranquilizers and other CNS depressants: Sedative effects potentiated MAOIs: Fatal interaction occurs Opioid analgesics like Buprenorphine, Butorphanol and Pentazocine: May precipitate withdrawal symptoms. Tranquilizers: Analgesia potentiated.
Storage:	Store between temperature 8℃ and 25℃ Protect from light Keep out of reach of children
Presentation:	10 ampoules of 2 mL in a plastic tray packed in printed carton

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